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25th Aug

Senior Protein Characterisation Scientist

— Leading Drug Discovery innovation

Competitive Salary
  • Fast growing and extremely innovative scale-up.
  • Utilising unique methods for drug discovery.
  • Strong career progression opportunities.
This fast-growing Drug Discovery scale-up in London, is building a platform to discover revolutionary medicines using machine learning. They have exciting growth plans for the next 18 months and are looking for an experienced and passionate Senior Protein Characterisation Scientist to join them on their mission as they combine Machine Learning (ML), robotic automation and synthetic biology to evolve next-generation protein therapeutics.
They are looking for someone who has significant industrial experience in biotherapeutic protein characterisation and are looking for a role where you can have a real impact on how things are done. Your expertise will be put to use to establish high quality characterisation assays, increase our QC capabilities, as well as identify and define capability development requirements for future asset discovery programs.

What you’ll be doing:
  • Develop robust high- and low-throughput and assay capabilities to characterise our target and candidate proteins.
  • Work with our automation team to automate and scale protein QC assays, ensuring high quality data generation suitable for machine learning and pre-clinical applications.
  • Integrate protein QC data and your knowledge of sequence-based developability liabilities into our machine learning models, in an iterative design-build-test-learn process.
  • Work closely with our internal Pipeline team to plan and review proposals for future projects, identifying priority areas for capability development within Protein Science.
  • There will be opportunity for technical mentorship of less experienced members of the team - we’re keen to develop our skills and learn from the best!
What experience you’ll need to apply:
  • You’re passionate about protein characterisation and keen to remain hands-on in the lab.
  • You’re an expert user of a range of industry-standard protein QC instruments and techniques. We’re particularly keen to hear from you if you have deep experience in SEC-UHPLC, LC-MS, DLS, or other similar biophysical QC techniques.
  • You have a wealth of antibody engineering knowledge to share, with expertise in humanisation, half-life extension, forced stability studies, and other developability considerations.
  • You enjoy shaking things up for the better, with experience of advocating for, implementing, and validating new protein characterisation technologies.
  • You have a track record of successfully training and developing less experienced team members, raising standards across the team.
  • You’re interested in or have previous experience of applying machine learning to tackle protein engineering challenges.
  • Previous experience of upstream/downstream protein production or working with HTP protein production platforms will be highly advantageous, although not required.
What you’ll get in return for your experience:

Be part of a great culture offering flexible working, 1-on-1 coaching, self-service study budgets, weekly team lunches and innovative drug discovery where your voice will be heard.
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Who's managing this role?

Zoe Davies

Zoe Davies

— Senior Recruiter Pharmaceutical & Life Sciences

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