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20th Aug

Senior Scientist, Immuno-Oncology

— Leading Drug Discovery innovation

Competitive with shares
  • Fast growing and extremely innovative scale-up.
  • Utilising unique methods for drug discovery.
  • Strong career progression opportunities.

This fast-growing Drug Discovery scale-up in London, is building a platform to discover revolutionary medicines using machine learning. They have exciting growth plans for the next 18 months and are looking for an experienced and passionate Senior Immuno-Oncology Scientist to join them on their mission as they combine Machine Learning (ML), robotic automation and synthetic biology to evolve next-generation protein therapeutics.
You’ll be a pivotal member of the wet lab team - an expert in flow cytometry, with a strong assay development background. You will have experience in an industrial drug discovery, particularly in the field of immuno-oncology/ T cell engagers.
Your role will be varied, with clear communication being critical to your day-to-day interactions with the team. Being able to integrate your workflow with other teams, along with the ability to share findings in an articulate manner, will help you to achieve success within this position.

What you’ll be doing:
  • As a senior member of the team in addition to running cell killing and potency assays, you will be responsible for planning, designing and directing complex screening experiments involving multiple methodologies and input from multiple contributors.
  • Develop cell-based assays to characterise novel biotherapeutics derived from thier bespoke antibody scaffold libraries. These assays will be both functional to determine potency and biophysical to look at aspects of developability.
  • You'll integrate protein characterisation assays into the workflows of the various projects.
  • Work closely with the automation engineers you will plan strategy for future automation, constantly thinking of new ways to develop and advance our capabilities.
  • Use your experience to help evaluate targets, design experiments and support project planning.
  • Analyse data and give expert guidance, both to team members and other functions within the company. Your ability to distil complexity into concise communications will be put to use every day.
  • Share your knowledge throughout the company and help to train others.
  • You'll create materials for communication of data to internal and external clients.
What experience you’ll need to apply:
  • You’ll have a PhD or relevant industrial experience, with a strong scientific background and extensive practical experience in immuno-oncology/ T cell biology.
  • Experience in flow cytometry, cell-based ELISA, cell viability assays, cell-based screening assays for preclinical drug discovery & functional validation.
  • You are aware of the state of the art in laboratory automation with practical experience of running liquid handling robots. You are always looking to develop new ways of automating and standardising science.
  • You will be a subject matter expert on cell based assays and how they can support drug discovery. You’ll have the ability to communicate clearly and effectively with specialists from your own and other fields (e.g. automation engineers, NGS and data scientists).
  • As an experienced mentor, you’ll have a track record of training more junior team members.
  • You'll have a working knowledge of biological drug discovery platforms, with experience of antibody drug developability a distinct advantage.
What you’ll get in return for your experience:

Be part of a great culture offering flexible working, 1-on-1 coaching, self-service study budgets, weekly team lunches and innovative drug discovery where your voice will be heard.
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Who's managing this role?

Roy Bennett

Roy Bennett

— Head of Science & Engineering Science & Innovation

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