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26th Jan

Scientist High Throughput Screening (HTS)

— disruptive Drug Discovery

Location:
London
Type:
Salary:
Competitive with Stock options & Flexi working

 

  • Fast growing and extremely innovative scale-up
  • Utilising unique methods for drug discovery
  • Strong career progression opportunities

This is an opportunity to join an exciting London based drug discovery innovator utilising machine learning to vastly improve the drug discovery process and produce more effective therapeutics worldwide. In line with growth, they are searching for a Scientist with strong Biochemical High Throughput Screening experience.

What you’ll be doing:

You’ll be a member of the wet lab team in HTS. You will have experience in industrial drug discovery and are now looking for a company to grow and evolve in. As one of the HTS Scientists, your industrial/ academic know-how will be essential to this role and your experience in assay development/ screening will be put to good use in their in-house wet lab. Whatever your previous experience includes, you’ll inject passion and energy into everything you do. You’ll enjoy fast-paced work, and you’ll have an endless hunger for knowledge, learning, and growth; all the qualities they celebrate!

What you’ll do in this role:

  • Develop a range of biochemical assays to characterise novel biotherapeutics derived from bespoke antibody scaffold libraries.
  • Optimise and validate these screens, using a range of statistics to be sufficiently robust and high-throughput to fuel project demand.
  • You will work closely with the automation team to automate and screen these assays.
  • You will integrate your workflows with their protein team to develop the seamless end-to-end screening platform.

What experience you will need to apply:

  • PhD or relevant industrial experience, with practical experience in HTS and/or biochemical assays.
  • Experience with 384-well biochemical assays (e.g.  FRET, HTRF, LANCE, NanoBRET, AlphaScreen, BLI, SPR).
  • The ability to explain scientific concepts to non-scientists, such as automation engineers.
  • You’ll have worked on projects that involved troubleshooting or optimising biochemical assays.

How you enjoy working

  • Comfortable with a rapid pace of work in a dynamic environment.
  • You work to the highest standards with high attention to detail, our data needs to be robust so that we can learn from it.
  • You’re happiest working in a collaborative context. If you love flying solo, this isn't the right role for you.
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