Molecular Biology jobs and careers
Molecular Biology is the study of the structure, composition and interactions of cellular molecules in living organisms, including the Biological Processes essential for the cell’s function and the relationship between DNA, RNA and Protein Synthesis.
Why consider a career in Molecular Biology?
Molecular Biologists research and experiment with the functions and biological laws of living cells. Molecular biologists look to isolate and purify components of the cell such as proteins and DNA which helps understand and conclude its function by identifying specific patterns in biological materials.
The work of a Molecular Biologist can be applied to a wide range of fields and applications, making it a very appealing career path. These range from drug discovery, genetic modification of crops, cell and gene therapy and production of cell-based clean meat which would reduce antibiotic presence in the food chain.
Working within this sector is very rewarding as you have the potential to significantly impact the wellbeing of humans, animals and the environment.
What a job or career in Molecular Biology may entail…
The work of a Molecular Biologist is often split between a laboratory, carrying out scientific experiments using techniques such as DNA cloning, Polymerase Chain Reaction, gel electrophoresis, molecular hybridization and mutagenesis, whereas the other time is spent analysing and interpreting biological data.
A career in molecular biology is appealing, as the future job prospects in the industry are increasing at an exponential rate.
Typical role titles include
Clinical Laboratory Technician
Clinical Research Specialist
Career progression example
Chief Scientific Officer (CSO)
Research Engineers/Junior Scientist with a PhD or Masters in Molecular Biology earn between £33 - £42k.
At the mid-experience-level, Molecular Scientists normally earn between £40k - £50K. Seniors to Principal Scientists normally earn between £50k - £65K.
Is it right for me? The skills it takes...
The following technologies and skills often appear on job descriptions;
PhD or Masters degree in Molecular Biology or Microbiology, PCR, qPCR, protein characterisation, Cell culture, Cell transfection, immunoassays, DNA sequencing, Molecular cloning techniques and RNA.
What qualifications does it take?
A PhD or Masters degree in Molecular Biology or Microbiology is usually essential, and quite often research work within a specialised field with molecular biology is desirable.
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— Leading Drug Discovery innovationLocation:LondonSalary:Competitive with sharesFast growing and extremely innovative scale-up. Utilising unique methods for drug discovery. Strong career progression opportunities. This fast-growing Drug Discovery scale-up in London, is building a platform to discover revolutionary medicines using machine learning. They have exciting growth plans for the next 18 months and are looking for an experienced and passionate Senior Immuno-Oncology Scientist to join them on their mission as they combine Machine Learning (ML), robotic automation and synthetic biology to evolve next-generation protein therapeutics.You’ll be a pivotal member of the wet lab team - an expert in flow cytometry, with a strong assay development background. You will have experience in an industrial drug discovery, particularly in the field of immuno-oncology/ T cell engagers.Your role will be varied, with clear communication being critical to your day-to-day interactions with the team. Being able to integrate your workflow with other teams, along with the ability to share findings in an articulate manner, will help you to achieve success within this position.What you’ll be doing: As a senior member of the team in addition to running cell killing and potency assays, you will be responsible for planning, designing and directing complex screening experiments involving multiple methodologies and input from multiple contributors. Develop cell-based assays to characterise novel biotherapeutics derived from thier bespoke antibody scaffold libraries. These assays will be both functional to determine potency and biophysical to look at aspects of developability. You'll integrate protein characterisation assays into the workflows of the various projects. Work closely with the automation engineers you will plan strategy for future automation, constantly thinking of new ways to develop and advance our capabilities. Use your experience to help evaluate targets, design experiments and support project planning. Analyse data and give expert guidance, both to team members and other functions within the company. Your ability to distil complexity into concise communications will be put to use every day. Share your knowledge throughout the company and help to train others. You'll create materials for communication of data to internal and external clients. What experience you’ll need to apply: You’ll have a PhD or relevant industrial experience, with a strong scientific background and extensive practical experience in immuno-oncology/ T cell biology. Experience in flow cytometry, cell-based ELISA, cell viability assays, cell-based screening assays for preclinical drug discovery & functional validation. You are aware of the state of the art in laboratory automation with practical experience of running liquid handling robots. You are always looking to develop new ways of automating and standardising science. You will be a subject matter expert on cell based assays and how they can support drug discovery. You’ll have the ability to communicate clearly and effectively with specialists from your own and other fields (e.g. automation engineers, NGS and data scientists). As an experienced mentor, you’ll have a track record of training more junior team members. You'll have a working knowledge of biological drug discovery platforms, with experience of antibody drug developability a distinct advantage. What you’ll get in return for your experience:Be part of a great culture offering flexible working, 1-on-1 coaching, self-service study budgets, weekly team lunches and innovative drug discovery where your voice will be heard.
— Leading Drug Discovery innovationLocation:LondonSalary:Very competitive with sharesPioneering Drug Discovery innovator.Fast growing scale-up.Inclusive and diverse culture.As a Principal Scientist - Antibody Engineering, you will be responsible for making sure the company designs the best drug candidates. You will be working with a talented team of scientists and engineers in London, to deliver ambitious internal and partnered programmes. You will bring significant experience of protein therapeutic discovery and development with a particular focus on single domain antibodies and multi-specifics. You will also be willing to think about better ways to solve complex protein engineering problems in this space. What you’ll be doing: Lead protein engineering efforts, designing the next generation of single domain and multi-specific drugs. Work hand-in-hand with data and wet lab scientists to design and deliver cutting edge protein engineering solutions. Liaise with partners in business development interactions and provide technical expertise to the design and execution of partner-led projects. Build on the progress already made and to help to shape ML capabilities for protein engineering. Coach and mentor members of the team in cutting edge protein engineering solutions. Advocate a drug discovery mindset in project design and execution, drive and maintain high standards for data generation. Be constantly on the lookout for the next advances in protein engineering and propose projects that will continuously improve our platform. What skills you’ll will need to apply: Significant experience of therapeutic protein discovery - taking molecules from design to pre-clinical studies. You will have a deep technical background in protein engineering, exemplified by a high-impact publication record and presentations at conferences. Experience of working with single domain antibodies and multivalent therapeutics. In particular knowledge of protein engineering for oncology therapeutics. Experience of leading and developing teams in a matrix environment. Excellent communication skills – able to explain complex ideas to non-experts. A knowledge and understanding of the use of advanced in silico protein design methodology. Experience of lab automation and running experiments at high throughput. Nice to haves You know how to work effectively within a startup organisation. Experience of using machine learning in protein engineering. What you’ll get in return for your experience:To be part of a brilliant and purpose driven team, for a company dedicated to have a positive impact on human health, with like-minded people. The company also offers flexible working (3 days per week working from home), self-study budgets, one to one coaching, and they are big on diversity!
— Genetic Bioscience innovatorLocation:BristolSalary:£40,000 - £50,000Senior Scientist Highly successful and fast-growing Bioscience innovator. Pioneering techniques within their field. An opportunity to make a significant impact. This is opportunity for a senior scientist to be part of rapidly growing product development, focused on microbiome modulation and bacterial control using highly innovative genome editing techniques. You will enjoy take a lead role in developing product candidates from proof-of-concept studies generated by the companion research team, through pilot scale fermentation to product formulation. It is expected the that you will be fully conversant with molecular biological tools to contribute to the design of candidates, making modifications that enhance stability and product yield whilst retaining full functionality. What you'll be doing: · Contribute to design of candidates by liaison with the Research team with reference to stability and yield. · Take existing commercial product candidates from the lab bench scale through process development using in-house small pilot scale production systems. · Design and test post-production processing and formulation options that improve product stability. Additionally, provide high-quality data appropriately presented to meet application development, regulatory dossier requirements and customer trials. · Work through CMO’s, CRO’s as needed to further scale-up product candidates. · Improve the product development time horizons by streamlining laboratory processes which will enable application. · Work closely with Research, Analytical and QC teams to help achieve the companies’ goals. What experience you’ll need to apply? · Experience in microbial molecular biology with reference to strain development. · Expertise in fermentation at least to laboratory small scale. · Appropriate academic credentials to at least PhD level. · Evidence of excellent problem-solving capabilities. · Proven application of analytical and reporting skills. · Leadership qualities to manage a small team, manage complex workstreams and excellent interpersonal skills. · Possess a good understanding of CRISPR, genetic transformation and the regulatory environment for biotech products. · Any relevant industrial R&D experience and an understanding of the food value chain Farm to Fork would be desirable. What you’ll get in return for your experience: Help contribute towards truly pioneering techniques, working on the key development of exciting products alongside a brilliant team of scientists. You’ll have the opportunity to also develop your career in a high-quality facility with links to a top 10 UK University. What’s next: Send your CV and we’ll get back to you shortly.
— Genetic Bioscience innovatorLocation:BristolSalary:£35,000 - £50,000Highly successful and fast-growing Bioscience innovator. Pioneering techniques within their field. An opportunity to make a significant impact. This is opportunity for a senior post-doctoral scientist to be part of a rapidly growing research and development focused on microbiome modulation and bacterial control using highly innovative genome editing techniques.The post holder will report to the Head of Research and R&D Director and will work effectively as part of a small team in Bristol, dedicated to improving existing and new products. It is expected candidates will be highly accomplished molecular biologists with abundant experience in areas such as DNA assembly, molecular cloning and the engineering of bacterial genomes and large plasmids.What you'll be doing: Play a pivotal role in the design, construction, and testing of new candidate products as part of the research team. Quickly generate high-quality and insightful data, information and reports that are effectively communicated to the rest of the team and line/senior management. Contribute to the design and delivery of technical strategies and project plans that deliver improvements with time and resource estimates. Interact with Development, Analytical and QC teams to ensure achievement of the company’s overall requirements. What experience you’ll need to apply? Highly proficient in microbial molecular biology with expertise in either CRISPR-Cas systems and their application in bacteria or knowledge of DNA delivery mechanisms (both would be ideal). PhD qualified ideally with some post-doc experience within a similar subject field. Evidence of excellent problem-solving capabilities and analytical skills. Potential to manage a small team, manage complex workstreams and excellent interpersonal skills. Any plasmid, gene transfer, recombineering, genome evolution, transposon or phage biology would be a bonus. Additionally, understanding of the food value chain Farm to Fork would also be desirable but not essential. What you’ll get in return for your experience:Help contribute towards truly pioneering techniques, working on the key development of exciting products alongside a brilliant team of scientists. You’ll have the opportunity to also develop your career in a high-quality facility with links to a top 10 UK University.What’s next:Send your CV and we’ll get back to you shortly.