Protein Science jobs and careers
Why consider a career as a Protein Scientist?
A career in Protein Science exposes you to an array of amazing opportunities. The industry is very rapidly expanding with the increase in preclinical drug discovery and the application of machine learning to protein science. Protein Scientists support drug discovery projects that transform healthcare and be a part of the journey to discover cures for untreatable diseases.
What a job or career in Protein Science may entail…
As a Protein Scientist, you will be working in a laboratory mostly involved in drug discovery projects. The area of “protein science” is very broad and varied.
Typical role titles include
Drug Discovery Scientist
Protein Production Scientist
Protein Purification Scientist
Protein Characterisation Scientist
Career progression example
Junior Protein Scientist
Senior Protein Scientist
Principal Protein Scientist
Head of Protein Science
Salaries are dependent on the company and the exact areas of responsibility of each role. Generally, roles based in Cambridge, London and Oxford will be higher paying than anywhere else in the UK as these are the hubs for science with many companies competing for top talent. The below are a rough benchmark.
Junior Protein Scientist – Usually someone who has a master’s degree with a year in industry or someone who has done a placement year. People can get into Protein Science directly from a master but would need to be highly relevant to the company. Salaries for these roles range from £25,000 to £30,000.
Protein Scientist – Usually someone who has a master’s and a couple of years’ experience, or someone who has done a PhD and is looking to go straight into industry. The salary guide for this is between £30,000 - £40,000.
Senior Protein Scientist - Usually someone who has a few years’ experience in Protein Science. This is normally someone who has a PhD with a postdoc that has been about 2/3 years or someone who has a master’s with about 5 years’ experience in industry. Salaries for these roles tend to be between £40,000 and £50,000.
Principal Protein Scientist - Usually someone who is a real expert in the field and has extensive experience working within the space. They tend to bring at least 10 years’ experience. Salaries for this kind of role could be between £50,000 - £70,000.
Head of Protein Science – Salaries for senior posts of this kind tend to sit between £70,000 to £90,000.
Is it right for me? The skills it takes...
There are a lot of different skills that can lead to different paths, but the typical skills listed on job specifications are:
- Protein expression, that can either be in bacterial, yeast, mammalian or insect expression systems.
- Protein purification using techniques such as FPLC, AKTA pure - chromatography (SEC, IEX, affinity etc) or filtration (TFF or UFDF).
- Protein cloning skills, using Gibson assembly, Golden gate.
- Characterisation assays to assess stability, purity and activity to QC and rank candidate protein using techniques such as ELISA, flow cytometry, cell viability assays etc.
- Protein Production.
- Cell Engineering, for the expression of novel proteins to target cells.
There is a range of different protein targets that can be worked on and they depend on the company, but these can be membrane proteins, monoclonal antibodies, multi-valent biologics, antibodies, T-cells, peptide-HLA’s and a large number of others. Most people in the space will have specific experience working within one of these and will then stay within this area for their whole career.
What qualifications does it take?
The majority of clients within in this field will look for a PhD or master’s, that is heavily focused on Protein Science, plus industry experience is a benefit depending on the level of the role.
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— Leading Drug Discovery innovatorLocation:LondonSalary:Competitive with sharesFast growing and extremely innovative scale-up Utilising unique methods for drug discovery Strong career progression opportunities This is an opportunity to join an exciting drug discovery innovator, offering market leading science and ambitious plans. To be as effective as possible, they have decided to have managers who focus entirely on management – giving teams the best possible management experience. As a drug discovery people manager, you’ll take on management responsibilities for a group within the drug discovery team. They are a multidisciplinary group of molecular biologists, phage display scientists, protein scientists, cell biologists and protein engineers, working together with colleagues in the dry lab to revolutionise drug discovery. You’ll also collaborate with the Head of Discovery, Principal Scientist, and senior individual contributors (ICs) to set strategy and define the roadmap. What you’ll be doing: Manage a group of 6-8 people to ensure they’re happy, motivated, focused and delivering incredible work. Use regular 1:1s to provide continuous feedback, ensure peak performance and recognise the individual strengths and contributions of direct reports. Grow and develop individuals on the team, using mentorship, coaching and sponsorship to help them learn or show their skills. Collaborate with the Head of Discovery, Principal Scientist, and senior ICs to make tactical decisions, drive standards and practices for work. Diagnose and resolve people problems between and within teams. Bring your experience of early-stage drug discovery to provide scientific direction to the team. Work closely with the talent team to attract, hire, onboard, and retain high potential team members from diverse backgrounds. What experience you’ll need to apply? You will have a strong biology background and have worked as Scientist, ideally within Drug Discovery in Pharma or Biotechs. What we are looking for first and foremost is exceptional management skills. You have an empathetic leadership style, and you build strong, effective relationships. You have solid experience working in multi-disciplinary teams and are keen to experiment beyond basic practices and improve your team's ways of working further. Degree or higher in a Biology related field. You have significant experience leading, coaching, and mentoring scientists (4 reports). Nice to haves Experience of early-stage biologics (large molecule) drug discovery. Well-developed project-management skills: being organised and disciplined, showing attention to detail, and following up to ensure the right results. What you’ll get in return for your experience To be part of a brilliant and purpose driven team, for a company dedicated to have a positive impact on human health, with like minded people. The company also offers flexible working, self-study budgets, one to one coaching, and they are big on diversity! What's next? For more information or to apply, apply directly to this advert to speak with Roy Bennett.
— Senior position in a fast-growing start-upLocation:CambridgeshireSalary:Competitive with great benefitsDirector of Laboratory Services • Fast-Growing start- up environment. • Positive, patient centred work environment. • Variety of tasks, responsibilities and development. This is an exciting opportunity to work in a fast-paced, high growth, start-up environment leading and directing the laboratory services division. Using lab-based pathology experience to manage overall lab operation and lab tasks including stock management, personnel supervision, regulatory and quality functions, and recruitment. What you’ll be doing: Manage and oversee laboratory operations and performance including, stock management, equipment purchase, personnel recruitment and training, process regulation and development, as well as ensuring compliance with lab standards and regulation. Establish and oversee communication with both internal and external stakeholders. Maintain quality of laboratory services by establishing and maintaining quality control and quality assurance programmes. Manage planning and operations within cost control, waste reduction, quality, safety, and complete on-time delivery. Ensure test methodologies and appropriate with the capability to provide reliable results for patient care. Ensure laboratory personnel are using test procedures and methods delivering accurate and reliable results. Monitor trends in utilisation of lab trends services reporting to senior and management teams. Budget, staff and equipment purchase management. Laboratory building maintenance including physical plant and ensuring lab conditions are appropriate. What they are looking for? BSc (preferably an MSc) in biological discipline. Registration with the Health Care Professional Council (HCPC) and registered with the institute of Biomedical Scientist. Experience on Laboratory management, ideally within a pathology laboratory. Experience of histopathology and cytological techniques desirable. Significant Team Management experience. Project Management, problem solving, team leadership and communication skills. What you’ll get in return for your experience: This is a chance to join and influence a growing start-up during a period of growth and development. You will be a key player in a fast-faced, high achieving company with great personal development opportunities. Share Options, Pension scheme, 25 days holiday, Health & Dental Insurance, Life Insurance and critical Illness cover, Cycle to Work Scheme and Company Laptop. What's next? For more information or to apply, apply directly to this advert to speak with Jazz Jones
— Global genetic bioscience innovationLocation:BristolSalary:£70,000 - £100,000Highly successful and fast-growing Bioscience innovator. Pioneering techniques within their field. An opportunity to make a significant impact. This is opportunity as a Research and Development Director to lead rapidly growing research and development focused on microbiome modulation and bacterial control using highly innovative genome editing techniques. The company is making significant success on a global basis with many countries looking to adopt their products and technology. What you'll be doing: Take existing commercial product candidates from the lab bench scale through process development to small pilot scale production runs, that are formulated appropriately for application development, regulatory and customer trials. Directly work through CMO’s & CRO’s as needed to further scale-up product candidates. Improve the product development time horizons by streamlining laboratory processes which will enable application. Innovate to create novel solutions and to bolster the company’s product candidates and create new product candidates that are supported by business case. Ensure reports, data, information is well written and presented from the team. Create new IP to add to our extensive IP estate and to protect innovation advances. Help drive and motive the current team of scientists and grow your team by recruiting talent where necessary. What experience you’ll need to apply? 5 to 10 years R&D experience in industry, ideally with significant biotechnology product development experience. Evidence of critical assessment of and design of reliable and meaningful product specification definition. Proven application of analytical methods throughout production, post-production processing and long-term storage for product yield and stability improvement. A broad understanding of biotechnology and its potential application to control or change microbiomes, an understanding of CRISPR, genetic transformation and the regulatory environment for biotech products. Leadership qualities – medium size team management, complex workstream management and an influential and motivational management style. Strong work ethic with a proven track record for solving scientific/production problems. An understanding of the food value chain Farm to Fork would be desirable. What you’ll get in return for your experience: Help contribute towards truly pioneering techniques, working on the key development of commercial projects alongside a brilliant team of scientists. You’ll have the opportunity to truly develop and shape the product. The role can be based in Bristol full time or 1 day per week, so plenty of flexibility if you live further away. What’s next? Send your CV via this advert and we’ll get back to you shortly.
— Leading Drug Discovery innovationLocation:LondonSalary:CompetitiveFast growing and extremely innovative scale-up. Utilising unique methods for drug discovery. Strong career progression opportunities. This is an opportunity to join an exciting London based drug discovery innovator utilising machine learning to vastly improve the drug discovery process and produce more effective therapeutics worldwide. In line with growth, they are looking for a highly motivated molecular biologist driven by cutting-edge high throughput sequencing method development and execution. As part of the NGS team you will help to develop and run the sequencing workflows to establish genotype-phenotype links that we use for building machine learning models. You’ll work with their dynamic R&D teams to drive the discovery and development of protein therapeutics for unmet medical needs. Sequencing is core to their Platform, so you’ll ensure that they produce high-quality data, on time. What you’ll be doing: Contribute to drug discovery projects by using short- and long-read sequencing technologies to analyse biologics repertoires as part of the directed evolution platform. Investigate, develop & onboard newly implemented or standard sequencing workflows and experimental techniques. Assist in planning the expansion of their internal sequencing capabilities. Strive to improve data quality and throughput by optimising established workflows from sample input to read output. QC analyse, interpret, and troubleshoot NGS runs working closely with the R&D teams. Mentor and support the training of technical and non-expert colleagues in NGS technologies. Collaborate with our Display, Data Science, Bioinformatic and Automation experts to help design protein libraries and screening strategies. Keep excellent experimental/data records for cross functional teamwork and project learnings. What experience you will need to apply: A PhD in molecular biology, genetics, biochemistry, or similar, or equivalent industry experience with significant expertise in NGS. The ability to generate and implement new ideas with excellent troubleshooting skills. Able to perform a wide range of molecular biology techniques such as nucleic acid isolation, multiplex PCR and RT. You’re comfortable with challenging yourself and acquiring unfamiliar scientific skills and knowledge. You have excellent organisational and time management skills, with demonstrated ability to prioritise, define timelines and deliver to these commitments. Nice to have skills: Previously worked with production-scale Illumina systems (NextSeq and above), or with TGS systems from other manufacturers (PacBio, Oxford Nanopore, etc), preferably employing laboratory automation. Experience in generation and analysis of amplicon sequencing and/or RNAseq data in directed evolution workflows. Developing strategies for immune repertoire e.g., TCR sequencing. Familiar with open-source software, bioinformatics tools and languages such as Python. How you enjoy working: You’re comfortable with a rapid pace of work in a dynamic environment. You work to the highest standards with high attention to detail, data needs to be robust so that they can learn from it. You’re happiest working in a collaborative context. If you love flying solo, this isn't the right role for you. You’re equally comfortable challenging as you are with being challenged. You get excited about learning new technologies and approaches. You want work to be meaningful and to be part of a business dedicated to having a positive impact on humanity. What you’ll get in return for your experience: To be part of a brilliant and purpose driven team, for a company dedicated to have a positive impact on human health, with like minded people. The company also offers flexible working, self-study budgets, one to one coaching, and they are big on diversity! What's next? For more information or to apply, apply directly to this advert to speak with Roy Bennett.
— Science, Sales and Account Management skills required for a Global Research CompanyLocation:North UKSalary:50,000Sales Account Manager Join a Global scientific Research Company in their UK team expansion. Autonomy over your UK accounts. Great sales-based bonus scheme. This is an exciting opportunity to join a global biotechnology group helping to expand their UK market within the life science, biologics and cell therapy spheres. This role is responsible for implementing sales and marketing strategy for products and services to achieve sales goals. This is a varied role with regular interaction with key clients and customers, along with contribution to team projects. What you’ll be doing: Contribute to the development and implementation of sale strategies and tactics for products/services, new markets and new applications. Work collaboratively with cross-functional teams to secure new business and maintain high standards with existing customers. Establish a comprehensive knowledge of competitor companies and use selling skills to win clients. Share market insight and customer feedback with relevant management and marketing teams. Develop and maintain warm relationships with key accounts. Accurately record interactions via CRM managing Sales Pipeline. What they are looking for: At least 2 years Sales/Account Manager experience within relevant Life Science, CRO, Biotech space. Academic Degree in relevant Life Science discipline, ideally a Master’s Degree with high level of technical expertise. Knowledge of the UK Biological and CRO Market – Gene Synthesis, Proteins, Peptides, Antibody and Cell Line products. Ability to operate effectively in an international business environment. Effective communication with external stakeholders as well as colleagues. What you’ll get in return for your experience: You will be a key player in their UK success with the flexibility to work autonomously managing client relations. Working mostly remotely with visits to an Oxfordshire office monthly. Ideal candidate will live near Bristol, Manchester or Sheffield - expected UK travel to visit clients and attend meetings. Basic Salary of £45,000-£55,000 with generous sales-base bonus scheme. What's next? For more information or to apply, apply directly to this advert to speak with Jazz Jones
— Quality and Regulatory Lead in a Global BiotechLocation:Kent and South WalesSalary:CompetitiveSite Quality Assurance / Regulatory Affairs Leader Leadership role in a high achieving team. Fast-paced, patient-centred work environment. Opportunity to work within a broad and varied remit. This is an opportunity to join a global biotechnology company within the Quality Team. This position will involve leadership of a team of Quality Professionals to ensure to ensure continuous quality and reliability of products. Great team structure in a fast-paced, customer focused business. What you’ll be doing Undertaking the position of Management Representative in line with ISO13485:2016 certification requirements. Deliver Quality Engineering support where needed. Line management of direct reports, including development and coaching of; Quality Engineers, Senior Quality Engineers, Quality Graduate roles & Product Stewardship Specialists. Participation in corporate audit programme ensuring adherence to all quality standards and regulations, as well as hosting external regulatory audits. Implement quality and operational improvement work programmes, monitor and measure key metrics to ensure business improvements. Regulate good Quality Engineering Practice (gQEP) within operational areas to ensure continulous improvement. Work with the Global Supplier Quality Leader to ensure all site processes are adhered to. Coordinate with site development teams to ensure Quality compliance and liaise with Quality Engineers to manage produce recalls when necessary. Take part in Material Review Board. Collaborate with Operations to coordinate and prioritise production processes to ensure that safe and effective products are produced. What they are looking for? At least 3 years in Quality/Regulatory role with knowledge of ISO13485 and other international quality system standards. Familiarity with leading and hosting Quality audits. Science Degree as well as further Quality Qualifications – Certified Lead Auditor. Lean (Six Sigma) desirable – analytical problem-solving skills with a risk base approach. Great team management, organisation, and communication skills. What you’ll get in return for your experience: A chance to join a global leader really making a difference in the work of biotechnology and diagnostics. Either located in Kent or South Wales – flexible and (part time) remote working available. Pension Scheme, generous annual leave, Life Assurance and Private Healthcare Scheme. What's next? For more information or to apply, apply directly to this advert to speak with Jazz Jones
— Disruptive Biotech innovatorLocation:HertfordshireSalary:£70,000 - £100,000Unique IP and offering. Very progressive Life Science technology. Grow your own team. This is an opportunity to join an exciting Bioprocessing innovator using a breakthrough platform to reduce the manufacturing costs within the Cell & Gene Therapy and Drug Discovery markets. In line with growth, they are seeking a Product Architect to manage the development and architecture of their products. As part of the executive management team, you will initially manage a team of 3 with rapid growth to 10. What you'll be doing: Create product architecture and gain an understanding of the technical and user requirements of the product. Design, build and execute product roadmaps. Manage the engineering team, growth, and function. Development and select third-party suppliers and relationships. Work with fellow executive management team on IP development and strategy. What experience you will need to apply: Extensive engineering product development for life science technology and/or applications. Proven leadership of teams 3 in size. Sound Quality Management Systems expertise. Used to managing engineering workshops or laboratories. Any experience of microfluidic technology would be beneficial but not essential. What you’ll get in return for your experience To be part of a brilliant team with significant input to success, for a company dedicated to having a positive impact on human health. Commutable from Cambridge, Stevenage, Luton, North London and Hertfordshire. What’s next? If you’re looking for an exciting and challenging role for disruptive technology for medical therapies, apply now.
— Medical Lead in a fast-growing healthcare organisation.Location:LondonSalary:Competitive• Join a company with a mission to help people lead healthier lives. • Fast-growing, innovative company with an energetic culture. • Improve healthcare systems with a digital, patient-centric approach. This is an opportunity to join a fast-growing health care company using digital tools to address some of the largest challenges facing healthcare and improve patient outcomes. You will be using your clinical knowledge and experience to work in partnership with the NHS to improve access to our offering, provide clinical guidance to our product development teams and offer remote patient care. Flexible and remote working available. What you'll be doing: • Support the team to win NHS contracts, write tenders and develop business cases. • Delivery of remote (email or phone) medical clinics including reviewing type 2 diabetic and obese patients ensuring appropriate prescribing. • Develop and influence the diabetes and obesity market within the UK. Gain an understanding of competitors and UK healthcare policy around weight and diabetes management. • Assist in the design of NHS medical pathways and input into the research strategy ensuring NICE requirements are met. • Clinical management and development of the diabetic nurse specialist and medical teams. • Support the Quality Lead in the CQC appraisal process as required. What experience you will need to apply: • Qualified Medical Doctor, either on the GMC GP Registered OR an endocrinology and diabetes mellitus register – you will have the option to practice clinically part time within this role, this will be discussed and agreed as part of your contract. • Strong commercial background with a competitive approach to team success. • Experience in clinical supervision and the delivery of clinical services within diabetes and weight management. • Strong communication skills (including virtual communication) and the ability to represent the company with professionalism. • Clinical research in obesity and type 2 diabetes along with a high level of understanding of digital health. What you’ll get in return for your experience: The opportunity to join a scale-up company with an energetic culture that is really making a difference within UK healthcare. Training and Development opportunities and a staff wellbeing programme and employee benefits scheme. Competitive salary, plus performance-based pay, employer contribution pension. London Office with flexible and remote working options.For more information, and to register intererst, get in touch with Jazz Jones.
— Leading Drug Discovery innovationLocation:LondonSalary:Competitive SalaryFast growing and extremely innovative scale-up. Utilising unique methods for drug discovery. Strong career progression opportunities. This fast-growing Drug Discovery scale-up in London, is building a platform to discover revolutionary medicines using machine learning. They have exciting growth plans for the next 18 months and are looking for an experienced and passionate Senior Protein Characterisation Scientist to join them on their mission as they combine Machine Learning (ML), robotic automation and synthetic biology to evolve next-generation protein therapeutics. They are looking for someone who has significant industrial experience in biotherapeutic protein characterisation and are looking for a role where you can have a real impact on how things are done. Your expertise will be put to use to establish high quality characterisation assays, increase our QC capabilities, as well as identify and define capability development requirements for future asset discovery programs. What you’ll be doing: Develop robust high- and low-throughput and assay capabilities to characterise our target and candidate proteins. Work with our automation team to automate and scale protein QC assays, ensuring high quality data generation suitable for machine learning and pre-clinical applications. Integrate protein QC data and your knowledge of sequence-based developability liabilities into our machine learning models, in an iterative design-build-test-learn process. Work closely with our internal Pipeline team to plan and review proposals for future projects, identifying priority areas for capability development within Protein Science. There will be opportunity for technical mentorship of less experienced members of the team - we’re keen to develop our skills and learn from the best! What experience you’ll need to apply: You’re passionate about protein characterisation and keen to remain hands-on in the lab. You’re an expert user of a range of industry-standard protein QC instruments and techniques. We’re particularly keen to hear from you if you have deep experience in SEC-UHPLC, LC-MS, DLS, or other similar biophysical QC techniques. You have a wealth of antibody engineering knowledge to share, with expertise in humanisation, half-life extension, forced stability studies, and other developability considerations. You enjoy shaking things up for the better, with experience of advocating for, implementing, and validating new protein characterisation technologies. You have a track record of successfully training and developing less experienced team members, raising standards across the team. You’re interested in or have previous experience of applying machine learning to tackle protein engineering challenges. Previous experience of upstream/downstream protein production or working with HTP protein production platforms will be highly advantageous, although not required. What you’ll get in return for your experience: Be part of a great culture offering flexible working, 1-on-1 coaching, self-service study budgets, weekly team lunches and innovative drug discovery where your voice will be heard.
— Leading Drug Discovery innovationLocation:LondonSalary:Competitive with sharesFast growing and extremely innovative scale-up. Utilising unique methods for drug discovery. Strong career progression opportunities. This fast-growing Drug Discovery scale-up in London, is building a platform to discover revolutionary medicines using machine learning. They have exciting growth plans for the next 18 months and are looking for an experienced and passionate Senior Immuno-Oncology Scientist to join them on their mission as they combine Machine Learning (ML), robotic automation and synthetic biology to evolve next-generation protein therapeutics.You’ll be a pivotal member of the wet lab team - an expert in flow cytometry, with a strong assay development background. You will have experience in an industrial drug discovery, particularly in the field of immuno-oncology/ T cell engagers.Your role will be varied, with clear communication being critical to your day-to-day interactions with the team. Being able to integrate your workflow with other teams, along with the ability to share findings in an articulate manner, will help you to achieve success within this position.What you’ll be doing: As a senior member of the team in addition to running cell killing and potency assays, you will be responsible for planning, designing and directing complex screening experiments involving multiple methodologies and input from multiple contributors. Develop cell-based assays to characterise novel biotherapeutics derived from thier bespoke antibody scaffold libraries. These assays will be both functional to determine potency and biophysical to look at aspects of developability. You'll integrate protein characterisation assays into the workflows of the various projects. Work closely with the automation engineers you will plan strategy for future automation, constantly thinking of new ways to develop and advance our capabilities. Use your experience to help evaluate targets, design experiments and support project planning. Analyse data and give expert guidance, both to team members and other functions within the company. Your ability to distil complexity into concise communications will be put to use every day. Share your knowledge throughout the company and help to train others. You'll create materials for communication of data to internal and external clients. What experience you’ll need to apply: You’ll have a PhD or relevant industrial experience, with a strong scientific background and extensive practical experience in immuno-oncology/ T cell biology. Experience in flow cytometry, cell-based ELISA, cell viability assays, cell-based screening assays for preclinical drug discovery & functional validation. You are aware of the state of the art in laboratory automation with practical experience of running liquid handling robots. You are always looking to develop new ways of automating and standardising science. You will be a subject matter expert on cell based assays and how they can support drug discovery. You’ll have the ability to communicate clearly and effectively with specialists from your own and other fields (e.g. automation engineers, NGS and data scientists). As an experienced mentor, you’ll have a track record of training more junior team members. You'll have a working knowledge of biological drug discovery platforms, with experience of antibody drug developability a distinct advantage. What you’ll get in return for your experience:Be part of a great culture offering flexible working, 1-on-1 coaching, self-service study budgets, weekly team lunches and innovative drug discovery where your voice will be heard.