R&D Jobs

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8 jobs found
  • 23rd Jul

    Principal Scientist - Immunology

    — Leading Drug Discovery innovation

    Location:
    London
    Type:
    Salary:
    Competitive Salary Shares
    Pioneering Drug Discovery innovator. Fast growing scale-up. Inclusive and diverse culture. As a Principal Scientist - Immunology, they are looking for a passionate Drug Discovery expert with a strong background in cellular and molecular biology/immunology, cellular assay development, high throughput screening, and Flow Cytometry. The focus of the role will be to effectively direct and support a multidisciplinary team of highly experienced scientists to deliver Immune Cell Engager programs into the pipeline providing a strategic insight. What you’ll be doing: As a senior member of the team you will be responsible for planning, designing and directing complex phenotypic screening experiments involving multiple methodologies and input from multiple contributors to interrogate complex biology related to immune cell engagers. Working closely with the automation team you will plan strategy for future automation, constantly thinking of new ways to develop and advance our capabilities. You'll generate and analyse data to be used in the machine learning process, and give expert guidance, both to team members and other functions within the company. Your ability to distil complexity into concise communications will be put to use every day. You'll share your knowledge throughout the company and help to train others. You'll create materials for communication of data to internal and external clients. What skills you’ll will need to apply: You’ll have a strong scientific background and extensive experience in drug discovery and immune cell. You will be the subject matter expert on phenotypic screening and how it can be applied to accelerate drug discovery. You’ll have the ability to communicate clearly and effectively with specialists from your own and other fields (e.g. automation engineers, NGS and data scientists). Proven record in antibody drug development and driving antibody therapeutics programs from early discovery into development stage. You are aware of the state of the art in laboratory automation with practical experience of running liquid handling robots. You are always looking to develop new ways of automating and standardising science. As an experienced mentor, you’ll have a track record of training more junior team members. Extensive experience developing high throughput biochemical and cellular assays including functional assays, binding assay, proliferation, and degradation. You’ll possess excellent communication skills and a strong network. Strong industry leadership experience, with high-impact publications and conference presentations.   What you’ll get in return for your experience: To be part of a brilliant and purpose driven team, for a company dedicated to have a positive impact on human health, with like-minded people. The company also offers flexible working (3 days per week working from home), self-study budgets, one to one coaching, and they are big on diversity!
  • 23rd Jul

    Laboratory Technician

    — Growing Biotech

    Location:
    London
    Type:
    Salary:
    Up to £25,000
    Be a key player in the success of a growing Biotech Be involved in the deployment of a product from clinical trials Make a real difference to patients lives This is an exciting opportunity to work as a Laboratory Technician in a rapidly growing therapeutics biotech that is developing next generation treatment for diseases.What you’ll be doing As a Lab Technician you be supporting the Biochemistry team that are focused on development of a first in class medical device. You will be performing experiments following SOP’s and protocols and will be fully based in the Laboratory. You will also be involved in operational laboratory tasks such as orders, managing inventory and laboratory management (i.e equipment maintenance).What experience you’ll need to apply? A life sciences degree with BSc/MSc. Two years’ experience working as a Laboratory Technician in a biochemistry lab. Experience running ELISAs. Excel experience. Nice to have: Surface functionalisation knowledge. Experience working with antibodies/proteins. Knowledge of Magnetic beads. Experience working with viral vectors. What you’ll get in return for your experience:You will be a key player in the success of the company that is looking to rapidly expand over the next couple of years. There is a competitive salary on offer with a good holiday and pension package.What's next?For more information or to apply, apply directly to this advert to speak with Zoe Davies
  • 23rd Jul

    Senior Research Scientist

    — Make a real difference

    Location:
    Cambridgeshire
    Type:
    Salary:
    Up to £50,000
    Growing biotech Competitive salary and package including private medical insurance, bonus and shares Great role for a human immunologist This is an exciting opportunity to join an innovative biotech that are developing a portfolio of first in class cancer therapies, and we are committed to delivering real impact on patient outcomes. They are a small but fast paced and dynamic company that offers a significant opportunity for growth and are backed by leading investors, and an experienced leadership team and Board. They are looking for a Senior Research Scientist who has extensive experience with human immunology specifically focusing on human immune cells such as macrophages and myeloid cells. What you’ll be doing Developing assays for macrophage and myeloid immune cells. Characterising therapeutic drug candidates in primary human immune cell assays by flow cytometry, imaging, and multi-omics assays Mammalian cells engineering What they are looking for? A PhD and/or postdoctoral experience in a relevant field. Assay development experience using primary human immune cells/cell lines including macrophages. Cell and tissue culture Genetic manipulation in cells such as RNAi and knock out Experience using phenotypic assays/flow cytometry for development of biochemical and cell assays for testing drug candidates What you’ll get in return for your experience:You will be a key player in their success. There is a yearly bonus, private medical insurance, sick pay, share options and a company pension. You may be required to work weekends, but this will be alternated. What's next?For more information or to apply, apply directly to this advert to speak with Zoe Davies   
  • 20th Jul

    Principal Scientist - Antibody Engineering

    — Leading Drug Discovery innovation

    Location:
    London
    Type:
    Salary:
    Very competitive with shares
    Pioneering Drug Discovery innovator.Fast growing scale-up.Inclusive and diverse culture.As a Principal Scientist - Antibody Engineering, you will be responsible for making sure the company designs the best drug candidates. You will be working with a talented team of scientists and engineers in London, to deliver ambitious internal and partnered programmes. You will bring significant experience of protein therapeutic discovery and development with a particular focus on single domain antibodies and multi-specifics. You will also be willing to think about better ways to solve complex protein engineering problems in this space. What you’ll be doing: Lead protein engineering efforts, designing the next generation of single domain and multi-specific drugs. Work hand-in-hand with data and wet lab scientists to design and deliver cutting edge protein engineering solutions. Liaise with partners in business development interactions and provide technical expertise to the design and execution of partner-led projects. Build on the progress already made and to help to shape ML capabilities for protein engineering. Coach and mentor members of the team in cutting edge protein engineering solutions. Advocate a drug discovery mindset in project design and execution, drive and maintain high standards for data generation. Be constantly on the lookout for the next advances in protein engineering and propose projects that will continuously improve our platform.  What skills you’ll will need to apply: Significant experience of therapeutic protein discovery - taking molecules from design to pre-clinical studies. You will have a deep technical background in protein engineering, exemplified by a high-impact publication record and presentations at conferences. Experience of working with single domain antibodies and multivalent therapeutics. In particular knowledge of protein engineering for oncology therapeutics. Experience of leading and developing teams in a matrix environment. Excellent communication skills – able to explain complex ideas to non-experts. A knowledge and understanding of the use of advanced in silico protein design methodology. Experience of lab automation and running experiments at high throughput.  Nice to haves You know how to work effectively within a startup organisation. Experience of using machine learning in protein engineering.  What you’ll get in return for your experience:To be part of a brilliant and purpose driven team, for a company dedicated to have a positive impact on human health, with like-minded people. The company also offers flexible working (3 days per week working from home), self-study budgets, one to one coaching, and they are big on diversity!
  • 6th Jul

    Senior Research Scientist

    — Genetic Bioscience innovator

    Location:
    Bristol
    Type:
    Salary:
    £35,000 - £50,000
    Highly successful and fast-growing Bioscience innovator. Pioneering techniques within their field. An opportunity to make a significant impact. This is opportunity for a senior post-doctoral scientist to be part of a rapidly growing research and development focused on microbiome modulation and bacterial control using highly innovative genome editing techniques.The post holder will report to the Head of Research and R&D Director and will work effectively as part of a small team in Bristol, dedicated to improving existing and new products. It is expected candidates will be highly accomplished molecular biologists with abundant experience in areas such as DNA assembly, molecular cloning and the engineering of bacterial genomes and large plasmids.What you'll be doing: Play a pivotal role in the design, construction, and testing of new candidate products as part of the research team. Quickly generate high-quality and insightful data, information and reports that are effectively communicated to the rest of the team and line/senior management. Contribute to the design and delivery of technical strategies and project plans that deliver improvements with time and resource estimates. Interact with Development, Analytical and QC teams to ensure achievement of the company’s overall requirements. What experience you’ll need to apply? Highly proficient in microbial molecular biology with expertise in either CRISPR-Cas systems and their application in bacteria or knowledge of DNA delivery mechanisms (both would be ideal). PhD qualified ideally with some post-doc experience within a similar subject field. Evidence of excellent problem-solving capabilities and analytical skills. Potential to manage a small team, manage complex workstreams and excellent interpersonal skills. Any plasmid, gene transfer, recombineering, genome evolution, transposon or phage biology would be a bonus. Additionally, understanding of the food value chain Farm to Fork would also be desirable but not essential. What you’ll get in return for your experience:Help contribute towards truly pioneering techniques, working on the key development of exciting products alongside a brilliant team of scientists. You’ll have the opportunity to also develop your career in a high-quality facility with links to a top 10 UK University.What’s next:Send your CV and we’ll get back to you shortly.
  • 17th Jun

    Research & Development Director

    — Global genetic bioscience innovation

    Location:
    Bristol
    Type:
    Salary:
    £70,000 - £100,000
      Highly successful and fast-growing Bioscience innovator. Pioneering techniques within their field. An opportunity to make a significant impact. This is opportunity as a Research and Development Director to lead rapidly growing research and development focused on microbiome modulation and bacterial control using highly innovative genome editing techniques. The company is making significant success on a global basis with many countries looking to adopt their products and technology. What you'll be doing:     Take existing commercial product candidates from the lab bench scale through process development to small pilot scale production runs, that are formulated appropriately for application development, regulatory and customer trials. Directly work through CMO’s & CRO’s as needed to further scale-up product candidates. Improve the product development time horizons by streamlining laboratory processes which will enable application. Innovate to create novel solutions and to bolster the company’s product candidates and create new product candidates that are supported by business case. Ensure reports, data, information is well written and presented from the team. Create new IP to add to our extensive IP estate and to protect innovation advances. Help drive and motive the current team of scientists and grow your team by recruiting talent where necessary. What experience you’ll need to apply?     5 to 10 years R&D experience in industry, ideally with significant biotechnology product development experience. Evidence of critical assessment of and design of reliable and meaningful product specification definition. Proven application of analytical methods throughout production, post-production processing and long-term storage for product yield and stability improvement. A broad understanding of biotechnology and its potential application to control or change microbiomes, an understanding of CRISPR, genetic transformation and the regulatory environment for biotech products. Leadership qualities – medium size team management, complex workstream management and an influential and motivational management style. Strong work ethic with a proven track record for solving scientific/production problems. An understanding of the food value chain Farm to Fork would be desirable. What you’ll get in return for your experience: Help contribute towards truly pioneering techniques, working on the key development of commercial projects alongside a brilliant team of scientists. You’ll have the opportunity to truly develop and shape the product.  The role can be based in Bristol full time or 1 day per week, so plenty of flexibility if you live further away.   What’s next? Send your CV via this advert and we’ll get back to you shortly.  
  • 17th Jun

    Senior Development Scientist

    — Global Biotech company in the diagnostics space

    Location:
    Kent
    Type:
    Salary:
    £30,000 - £38,000
    Working on a full product pipeline as part of a global diagnostics company. Fast-paced, patient-centred work environment. Variety of daily tasks and development opportunities. This is an opportunity to join a global diagnostics company without the corporate feel. As the Senior Development Scientist, you will be part of the technical development team working alongside the Production Department managing New Product Development, unique projects and Continuous Improvement Projects. The role includes a variety of design and development activities, across the full product pipeline, alongside team management and laboratory supervising.What you'll be doing: Plan and complete Technical Development projects, maintaining appropriate regulatory records, and sticking to timescale requirements. Design and execution of experimental work, managing own projects alongside those of the team. Supervise the team to meet targets set out in Project plan, evaluating project and team results throughout development. Accurately record and maintain details of all experimental work, preparing and reviewing data and documentation where required. Uphold a high standard of laboratory tidiness and organisation. Help recruit, train, and manage team members as well as contribute to internal meetings and liaise with external customers. Support other teams with technical expertise and represent the company at national and international meetings where required. What experience you will need to apply: Science based degree, ideally masters or higher. Protein Purification expertise and laboratory experience – ideally within protein and recombinant expression systems. New Product Development experience. Team and project management experience with high level organisational skills. What you’ll get in return for your experience:To be part of a high-achieving, international company with a thriving team environment, private health care scheme, Life Assurance, contributory pension scheme and generous annual leave package. Salary £30,000 – £38,000.Commutable from Kent, Maidstone, Canterbury, Sevenoaks, Southeast London.What’s next?If you’re looking for an exciting and challenging Senior Development Scientist role speak to Jazz Jones.
  • 10th Jun

    Product Architect

    — Disruptive Biotech innovator

    Location:
    Hertfordshire
    Type:
    Salary:
    £70,000 - £100,000
      Unique IP and offering. Very progressive Life Science technology. Grow your own team. This is an opportunity to join an exciting Bioprocessing innovator using a breakthrough platform to reduce the manufacturing costs within the Cell & Gene Therapy and Drug Discovery markets. In line with growth, they are seeking a Product Architect to manage the development and architecture of their products. As part of the executive management team, you will initially manage a team of 3 with rapid growth to 10. What you'll be doing:     Create product architecture and gain an understanding of the technical and user requirements of the product. Design, build and execute product roadmaps. Manage the engineering team, growth, and function. Development and select third-party suppliers and relationships. Work with fellow executive management team on IP development and strategy. What experience you will need to apply:     Extensive engineering product development for life science technology and/or applications. Proven leadership of teams 3 in size. Sound Quality Management Systems expertise. Used to managing engineering workshops or laboratories. Any experience of microfluidic technology would be beneficial but not essential. What you’ll get in return for your experience To be part of a brilliant team with significant input to success, for a company dedicated to having a positive impact on human health. Commutable from Cambridge, Stevenage, Luton, North London and Hertfordshire. What’s next? If you’re looking for an exciting and challenging role for disruptive technology for medical therapies, apply now.  
8 jobs found
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